RI-1
≥98%
Reagent
Code: #77757
CAS Number
415713-60-9
science Other reagents with same CAS 415713-60-9
blur_circular Chemical Specifications
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Molecular Information
Weight
361.61 g/mol
Formula
C₁₄H₁₁Cl₃N₂O₃
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Storage & Handling
Storage
-20°C
description Product Description
RI-1 is primarily used in scientific research, particularly in the field of DNA repair studies. It is known to inhibit the activity of the Mre11-Rad50-Nbs1 (MRN) complex, which plays a critical role in the cellular response to DNA double-strand breaks. By inhibiting this complex, RI-1 helps researchers understand the mechanisms of DNA repair pathways, including homologous recombination. This makes it a valuable tool in studying cancer biology, as defects in DNA repair mechanisms are often associated with tumor development and resistance to treatments like chemotherapy and radiation. Additionally, RI-1 is used to explore potential therapeutic strategies targeting DNA repair processes in various diseases.
format_list_bulleted Product Specification
| Test Parameter | Specification |
|---|---|
| Appearance | yellow to orange powder |
| Purity | 97.5-100 |
| Solubility | DMSO: 10 mg/mL, clear |
| Infrared Spectrum | Conforms to Structure |
| NMR | Conforms to Structure |
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