SB-277011 hydrochloride is primarily used in research settings to study the role of dopamine D3 receptors in the brain. It acts as a selective antagonist, helping scientists understand the receptor's involvement in various neurological and psychiatric conditions. This compound is particularly valuable in exploring addiction mechanisms, as dopamine D3 receptors are implicated in drug-seeking behaviors and reward pathways. Additionally, it aids in investigating potential therapeutic strategies for Parkinson's disease, schizophrenia, and other disorders linked to dopamine dysregulation. Its application extends to behavioral studies, where it helps elucidate the relationship between dopamine D3 receptors and cognitive or motor functions.