Used in research settings as a selective antagonist for α_2A-adrenergic receptors, aiding in the study of adrenergic pathways related to blood pressure regulation, sedation, neurotransmitter modulation, and central nervous system functions. Its high selectivity helps distinguish α_2A effects from other α₂ subtypes, making it valuable in pharmacological, cardiovascular, and neurochemical experiments. Also employed in radiolabeled form to assess receptor binding and distribution. Not intended for therapeutic use.