Retagliptin phosphate is primarily used in the management of type 2 diabetes. It functions as a dipeptidyl peptidase-4 (DPP-4) inhibitor, which helps regulate blood sugar levels by increasing the release of insulin and decreasing the production of glucagon. This dual action aids in maintaining optimal glucose levels in the bloodstream, making it an effective treatment option for individuals with diabetes. It is often prescribed as part of a comprehensive diabetes management plan, which may include diet, exercise, and other medications. Retagliptin phosphate is particularly beneficial for patients who require a stable and sustained approach to glucose control, reducing the risk of hyperglycemia and its associated complications.