Used in research to study guanylyl cyclase C (GC-C) receptor function and signaling pathways. Commonly applied in drug development for gastrointestinal disorders, including irritable bowel syndrome and chronic constipation, by serving as a model system to evaluate the activity of GC-C agonists. Also utilized in toxicology studies to assess the effects of bacterial enterotoxins that target the GC-C receptor. Supports high-throughput screening of compounds affecting cyclic GMP production.