AG-1478

>98%

Reagent Code: #99438
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CAS Number 153436-53-4

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 315.75 g/mol
Formula C₁₆H₁₄ClN₃O₂
inventory_2 Storage & Handling
Storage -20℃

description Product Description

AG-1478 is widely used in research settings as a selective inhibitor of the epidermal growth factor receptor (EGFR) tyrosine kinase. It is particularly valuable in studying the role of EGFR in cellular processes such as proliferation, differentiation, and survival. Researchers utilize AG-1478 to investigate its effects on cancer cell lines, as EGFR signaling is often dysregulated in various types of cancers. By inhibiting EGFR, AG-1478 helps in understanding the mechanisms of tumor growth and in evaluating potential therapeutic strategies. Additionally, it is employed in studies related to wound healing and tissue regeneration, where EGFR signaling plays a critical role. Its application extends to neuroscience research, where it is used to explore EGFR's involvement in neuronal development and function. Overall, AG-1478 serves as a crucial tool in biomedical research for dissecting EGFR-related pathways and their implications in health and disease.

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Test Parameter Specification
Appearance Faint yellow to yellow powder or crystals
Purity 98-100
NMR Consistent with structure
Infrared Spectrum Conforms to Structure

shopping_cart Available Sizes & Pricing

Size Availability Unit Price Quantity
inventory bulk
10-20 days ฿0.00
inventory 50mg
10-20 days ฿25,870.00
inventory 10mg
10-20 days ฿5,740.00
AG-1478
AG-1478 is widely used in research settings as a selective inhibitor of the epidermal growth factor receptor (EGFR) tyrosine kinase. It is particularly valuable in studying the role of EGFR in cellular processes such as proliferation, differentiation, and survival. Researchers utilize AG-1478 to investigate its effects on cancer cell lines, as EGFR signaling is often dysregulated in various types of cancers. By inhibiting EGFR, AG-1478 helps in understanding the mechanisms of tumor growth and in evaluating potential therapeutic strategies. Additionally, it is employed in studies related to wound healing and tissue regeneration, where EGFR signaling plays a critical role. Its application extends to neuroscience research, where it is used to explore EGFR's involvement in neuronal development and function. Overall, AG-1478 serves as a crucial tool in biomedical research for dissecting EGFR-related pathways and their implications in health and disease.
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