RHC 80267 is primarily utilized in biochemical research as a selective inhibitor of diacylglycerol lipase (DAGL), an enzyme involved in the biosynthesis of endocannabinoids. By inhibiting DAGL, it helps researchers study the role of endocannabinoids in various physiological processes, such as neurotransmission, inflammation, and pain regulation. This compound is particularly valuable in neuroscience and pharmacology for understanding the endocannabinoid system's impact on brain function and behavior. Additionally, it is used in experimental models to explore potential therapeutic targets for conditions like chronic pain, neurodegenerative diseases, and mood disorders. Its specificity makes it a crucial tool for dissecting the complex signaling pathways mediated by endocannabinoids.