(-)-WIN 55,212-3 mesylate is primarily used in research settings to study the endocannabinoid system and its effects on the central nervous system. It acts as a potent cannabinoid receptor agonist, making it valuable for investigating the physiological and pharmacological roles of CB1 and CB2 receptors. This compound is often utilized in preclinical studies to explore its potential therapeutic applications, such as pain management, neuroprotection, and anti-inflammatory effects. Additionally, it serves as a tool to understand the mechanisms underlying cannabinoid-mediated behaviors and signaling pathways in various disease models.