JWH 213 is primarily used in scientific research to study the endocannabinoid system and its interactions with cannabinoid receptors. It serves as a tool to investigate the pharmacological effects of synthetic cannabinoids, particularly their binding affinity and activity at CB1 and CB2 receptors. Researchers utilize it to explore potential therapeutic applications, such as pain management, anti-inflammatory effects, and neurological disorders. Additionally, it aids in understanding the structural-activity relationship of cannabinoids, which is crucial for developing new drugs with targeted effects. Outside of research, its use is not approved for medical or recreational purposes due to potential risks and lack of comprehensive safety data.