SB408124

99%

Reagent Code: #102499
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CAS Number 288150-92-5

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 356.37 g/mol
Formula C₁₉H₁₈F₂N₄O
badge Registry Numbers
MDL Number MFCD06411575
inventory_2 Storage & Handling
Storage -20℃

description Product Description

SB408124 is a selective non-peptide antagonist of the orexin-2 (OX2) receptor (pKi = 7.9), with much lower affinity for the orexin-1 (OX1) receptor. It is primarily used in research to investigate the orexin system's role in regulating sleep-wake cycles, arousal, feeding behavior, and stress responses. This compound serves as a valuable tool in pharmacological studies exploring potential therapies for disorders such as narcolepsy, insomnia, obesity, and addiction. Applications include in vitro receptor binding assays, functional studies on G-protein coupled receptor signaling, and in vivo models assessing effects on locomotor activity, sleep architecture, and metabolic processes.

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Size Availability Unit Price Quantity
inventory 1mg
10-20 days ฿1,719.00

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