Sch-42495 racemate is primarily utilized in pharmaceutical research and development, particularly in the study of cardiovascular diseases. It acts as a potent endothelin receptor antagonist, making it valuable for investigating the role of endothelin in conditions such as hypertension, heart failure, and pulmonary arterial hypertension. Researchers use this compound to explore its potential in blocking endothelin-mediated vasoconstriction, which can help in understanding and developing treatments for vascular disorders. Additionally, it serves as a critical tool in preclinical studies to evaluate the efficacy and safety of new therapeutic agents targeting the endothelin pathway.