SDZ-MKS 492 is primarily utilized in the field of medical research, particularly in the study of cardiovascular diseases. It is known for its potential role as a selective endothelin receptor antagonist, which makes it valuable in investigating the mechanisms of endothelin-mediated processes. Researchers use this compound to explore its effects on blood pressure regulation, vascular resistance, and heart function, providing insights into potential therapeutic applications for conditions such as hypertension and heart failure. Additionally, it is employed in preclinical studies to evaluate its efficacy and safety profile, contributing to the development of novel treatments targeting the endothelin system.