Used primarily in research settings as a selective endothelin receptor antagonist, particularly targeting the ETA receptor subtype. This compound has been investigated for its potential in studying cardiovascular conditions, including hypertension and vasospasm, due to its ability to block the vasoconstrictive effects of endothelin-1. It has also been utilized in experimental models to explore the role of endothelin in renal function and ischemia-reperfusion injury. Its application remains confined to preclinical research, aiding in the understanding of endothelin-mediated physiological and pathological processes.