E-Toxate Reagent derived from Limulus polyphemus is primarily used in the detection of bacterial endotoxins. This application is critical in the pharmaceutical and medical device industries to ensure products are free from harmful bacterial contamination. The reagent reacts with endotoxins to produce a measurable response, making it an essential tool for quality control. It is widely employed in the Limulus Amebocyte Lysate (LAL) test, which is a standard method for endotoxin testing in injectable drugs, vaccines, and medical equipment. Its high sensitivity and specificity make it indispensable for maintaining safety and compliance with regulatory standards. Additionally, it is used in research laboratories to study bacterial infections and immune responses.