E-toxate reagent derived from Limulus polyphemus is widely used in the pharmaceutical and medical industries for the detection of bacterial endotoxins. It plays a critical role in ensuring the safety of injectable drugs, medical devices, and other sterile products by identifying the presence of harmful endotoxins that can cause fever or septic shock in patients. This reagent is a key component of the Limulus Amebocyte Lysate (LAL) test, which is the gold standard for endotoxin testing due to its high sensitivity and reliability. Additionally, it is employed in quality control processes during the production of vaccines, biologics, and other therapeutics to meet regulatory standards and ensure product safety. Its application is essential in maintaining the sterility and efficacy of medical products.