Used in neuroscience research to measure BACE (beta-secretase) enzyme activity in mouse models, particularly in studies related to Alzheimer’s disease. Helps assess the effectiveness of potential therapeutic compounds by quantifying changes in BACE levels in brain tissue or biological fluids. Enables high-throughput screening in drug development and supports investigation into the amyloid pathway. Provides a reliable, sensitive method for monitoring disease progression and treatment response in preclinical studies.