Used in biomedical research to quantify heparanase enzyme levels in cell cultures, tissue extracts, and biological fluids such as serum or urine. Enables study of heparanase involvement in cancer progression, inflammation, and angiogenesis. Supports evaluation of drug candidates targeting heparanase activity in therapeutic development. Facilitates investigation of extracellular matrix degradation and basement membrane disruption in disease models. Commonly applied in oncology, immunology, and pharmacology research settings.