Used in biochemical and plant research to quantify Caffeic Acid-O-methyltransferase (COMT) enzyme levels in plant samples. Helps study lignin biosynthesis pathways, which are critical for understanding plant cell wall structure and improving biofuel production. Widely applied in agricultural research to evaluate genetic modifications aimed at reducing lignin content for better biomass digestibility. Also supports studies on plant defense mechanisms and stress responses, as COMT activity is linked to phenylpropanoid metabolism. The ELISA format allows high-throughput, sensitive detection in laboratory settings.