Used in research to detect and quantify phosphorylation levels of Inositol-requiring enzyme 1 (IRE1) in mouse models, particularly in studies related to endoplasmic reticulum (ER) stress and the unfolded protein response (UPR). This ELISA kit enables scientists to assess activation of the IRE1 signaling pathway, which plays a key role in cellular stress responses, inflammation, and apoptosis. It is widely applied in preclinical studies of metabolic diseases, neurodegenerative disorders, diabetes, and cancer, where ER stress is implicated in disease progression. The kit supports high-throughput analysis of tissue lysates or cell extracts, providing a reliable tool for monitoring IRE1 activity in experimental conditions involving drug treatments, genetic modifications, or disease modeling in mice.