Used in neuroscience and Alzheimer’s disease research to quantify γ-secretase activity in cell cultures, tissue samples, and biological fluids. Enables researchers to study the enzyme's role in amyloid-beta peptide production, a key factor in Alzheimer’s pathology. Supports drug development by allowing evaluation of γ-secretase inhibitors or modulators in preclinical studies. Provides a reliable, high-throughput method for measuring changes in γ-secretase levels under various experimental conditions, aiding in understanding cellular signaling pathways, including Notch processing. Widely used in academic labs, pharmaceutical research, and biomarker validation studies.