3-Acetyl-5-chlorothiophene-2-sulfonamide
98%
Reagent
Code: #136128
CAS Number
160982-10-5
blur_circular Chemical Specifications
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Molecular Information
Weight
239.7 g/mol
Formula
C₆H₆ClNO₃S₂
thermostat
Physical Properties
Boiling Point
453ºC
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Storage & Handling
Density
1.583g/cm3
Storage
Room temperature, dry
description Product Description
Used as a key intermediate in the synthesis of pharmaceutical agents, particularly in the development of carbonic anhydrase inhibitors which are applied in the treatment of glaucoma and certain types of epilepsy. Its structure allows for selective binding to enzyme active sites, enhancing therapeutic efficacy. Also employed in the preparation of diuretic drugs due to its sulfonamide functional group. The chloro and acetyl substituents provide sites for further chemical modification, making it valuable in medicinal chemistry for structure-activity relationship studies.
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