Werner syndrome RecQ helicase-IN-1
≥95%
Reagent
Code: #245582
CAS Number
2869954-34-5
science Other reagents with same CAS 2869954-34-5
blur_circular Chemical Specifications
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Molecular Information
Weight
702.0833 g/mol
Formula
C₃₁H₃₁ClF₃N₉O₅
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Storage & Handling
Density
1.58±0.1 g/cm3(Predicted)
Storage
2-8°C
description Product Description
Used in research to study DNA repair mechanisms and cellular aging. It inhibits the Werner syndrome protein (WRN), a helicase involved in maintaining genomic stability. By targeting WRN, this compound helps investigate cancer cell vulnerabilities, especially in microsatellite-unstable cancers that rely on WRN for survival. It is also employed to explore the role of RecQ helicases in replication stress and potential therapeutic strategies in oncology.
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