N-[1-(1H-1,3-benzodiazol-2-yl)-3-(methylsulfanyl)propyl]-3-methyl-1-benzofuran-2-carboxamide
95%
Reagent
Code: #245664
CAS Number
851453-95-7
science Other reagents with same CAS 851453-95-7
blur_circular Chemical Specifications
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Molecular Information
Weight
379.48 g/mol
Formula
C₂₁H₂₁N₃O₂S
thermostat
Physical Properties
Boiling Point
666.6±55.0 °C(Predicted)
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Storage & Handling
Density
1.292±0.06 g/cm3(Predicted)
Storage
-20°C, Sealed, Dry
description Product Description
Used in pharmaceutical research as a potent and selective inhibitor of soluble epoxide hydrolase (sEH), this compound plays a key role in modulating biological pathways related to inflammation, pain, and cardiovascular function. Its primary application lies in the development of therapies for inflammatory diseases, neuropathic pain, and hypertension due to its ability to stabilize endogenous epoxy fatty acids, which have anti-inflammatory and vasodilatory effects. It is also employed as a reference compound in enzyme activity assays and metabolic studies involving sEH inhibition. Due to its favorable pharmacokinetic profile in preclinical models, it serves as a lead structure in medicinal chemistry for optimizing new drug candidates targeting chronic inflammatory and metabolic disorders.
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