DHODH-IN-14 is primarily used in research settings to study its potential as an inhibitor of the dihydroorotate dehydrogenase (DHODH) enzyme. This enzyme plays a critical role in the de novo pyrimidine biosynthesis pathway, which is essential for DNA and RNA synthesis. By inhibiting DHODH, this compound is explored for its ability to suppress cell proliferation, particularly in rapidly dividing cells such as cancer cells or immune cells involved in autoimmune diseases. Researchers are investigating its efficacy in preclinical models of cancer, autoimmune disorders, and viral infections, where targeting pyrimidine synthesis could offer therapeutic benefits. Additionally, it serves as a tool compound to better understand the biological mechanisms of DHODH and its role in cellular processes.