Jarin-1 is primarily utilized in biochemical research as a selective inhibitor of acyl protein thioesterase 1 (APT1), an enzyme involved in the depalmitoylation of proteins. This compound is particularly valuable in studies aimed at understanding the role of protein palmitoylation in cellular signaling pathways. By inhibiting APT1, researchers can investigate the effects of altered palmitoylation on protein function, localization, and interactions within cells. Jarin-1 is also used in the development of therapeutic strategies targeting diseases where protein palmitoylation is dysregulated, such as cancer and neurological disorders. Its application extends to the study of lipid modifications in proteins, providing insights into the complex mechanisms of post-translational modifications and their impact on cellular processes.