Skp2 inhibitor C1 (SKPin C1) is primarily used in research to study the role of the Skp2 protein in cellular processes, particularly in cancer biology. It effectively inhibits Skp2, a key component of the SCF complex, which is involved in the ubiquitination and degradation of tumor suppressor proteins like p27. By blocking Skp2, this compound helps researchers investigate its impact on cell cycle regulation, apoptosis, and tumor growth inhibition. It is a valuable tool for exploring potential therapeutic strategies targeting Skp2 in cancers where it is overexpressed, such as prostate, breast, and lung cancers. Additionally, it aids in understanding the molecular mechanisms underlying Skp2-mediated oncogenesis and its potential as a drug target.