APX-115 is primarily used in research and therapeutic applications, particularly in the field of oxidative stress-related diseases. It functions as a potent inhibitor of NADPH oxidase (NOX) enzymes, which play a key role in generating reactive oxygen species (ROS). By inhibiting NOX, APX-115 helps reduce oxidative damage in cells, making it a promising candidate for treating conditions such as chronic kidney disease, diabetic complications, and inflammatory disorders. Its application extends to preclinical studies focused on understanding and mitigating the impact of oxidative stress in various pathological states. Additionally, APX-115 is being explored for its potential in protecting against tissue damage caused by ischemia-reperfusion injury, a common issue in organ transplantation and cardiovascular diseases.