BMS687453
10mM in DMSO
Reagent
Code: #142729
CAS Number
1000998-59-3
blur_circular Chemical Specifications
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Molecular Information
Weight
444.86 g/mol
Formula
C₂₂H₂₁ClN₂O₆
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Storage & Handling
Storage
-20°C
description Product Description
Used in research as a potent and selective inhibitor of phosphodiesterase 10A (PDE10A), an enzyme primarily expressed in the brain, particularly in the striatum. It is investigated for its potential in treating neurological and psychiatric disorders such as schizophrenia, Huntington's disease, and other conditions involving dysregulation of the dopaminergic and glutamatergic systems. Due to its ability to modulate intracellular signaling pathways by increasing cyclic adenosine monophosphate (cAMP) levels, it serves as a tool compound in preclinical studies to understand PDE10A function and evaluate therapeutic strategies targeting cognitive and motor symptoms. Not intended for human use outside of experimental settings.
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