BMS687453

10mM in DMSO

Reagent Code: #142729
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CAS Number 1000998-59-3

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 444.86 g/mol
Formula C₂₂H₂₁ClN₂O₆
inventory_2 Storage & Handling
Storage -20°C

description Product Description

Used in research as a potent and selective inhibitor of phosphodiesterase 10A (PDE10A), an enzyme primarily expressed in the brain, particularly in the striatum. It is investigated for its potential in treating neurological and psychiatric disorders such as schizophrenia, Huntington's disease, and other conditions involving dysregulation of the dopaminergic and glutamatergic systems. Due to its ability to modulate intracellular signaling pathways by increasing cyclic adenosine monophosphate (cAMP) levels, it serves as a tool compound in preclinical studies to understand PDE10A function and evaluate therapeutic strategies targeting cognitive and motor symptoms. Not intended for human use outside of experimental settings.

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Size Availability Unit Price Quantity
inventory 1ml
10-20 days ฿6,930.00

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