Used in research to study inflammatory processes, particularly in mast cell-related diseases such as asthma, allergic reactions, and autoimmune disorders. Plays a role in tissue remodeling and fibrosis, making it a target for drug development in cardiovascular diseases and chronic skin conditions. Also investigated for its involvement in angiotensin II production, offering potential therapeutic pathways in hypertension and heart failure. Employed in enzyme activity assays and inhibitor screening for pharmaceutical applications.