Selisistat S-enantiomer is primarily used in research focused on aging and neurodegenerative diseases. It acts as a potent and selective inhibitor of SIRT1, a protein involved in cellular regulation and longevity. This compound is valuable in studying the role of SIRT1 in processes like DNA repair, metabolism, and stress resistance. Its applications extend to investigating potential therapeutic strategies for conditions such as Huntington's disease, where SIRT1 modulation may offer neuroprotective benefits. Additionally, it aids in exploring the broader implications of sirtuin activity in cancer, diabetes, and other age-related disorders.