Ethyl 2-amino-5-iodo-4-(trifluoromethyl)benzoate
95%
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description Product Description
Used as a key intermediate in the synthesis of fluorinated pharmaceuticals and agrochemicals due to the presence of reactive functional groups, including the amino and iodo substituents. The electron-withdrawing trifluoromethyl group enhances metabolic stability, making this compound valuable in the development of bioactive molecules. It is particularly useful in cross-coupling reactions, such as Suzuki or Heck reactions, where the iodine moiety serves as a site for palladium-catalyzed bond formation. The ester group allows for further derivatization, enabling the construction of complex heterocyclic systems commonly found in medicinal chemistry. Its structure supports the design of compounds with improved lipophilicity and binding affinity, often explored in the research of CNS agents and kinase inhibitors.
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