Ethyl 2-amino-5-iodo-4-(trifluoromethyl)benzoate

95%

Reagent Code: #129695
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CAS Number 1131587-57-9

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 359.08 g/mol
Formula C₁₀H₉F₃INO₂
badge Registry Numbers
MDL Number MFCD11110757
thermostat Physical Properties
Boiling Point 360.3±42.0 °C(Predicted)
inventory_2 Storage & Handling
Density 1.780±0.06 g/cm3(Predicted)
Storage Room temperature, light-proof, inert gas

description Product Description

Used as a key intermediate in the synthesis of fluorinated pharmaceuticals and agrochemicals due to the presence of reactive functional groups, including the amino and iodo substituents. The electron-withdrawing trifluoromethyl group enhances metabolic stability, making this compound valuable in the development of bioactive molecules. It is particularly useful in cross-coupling reactions, such as Suzuki or Heck reactions, where the iodine moiety serves as a site for palladium-catalyzed bond formation. The ester group allows for further derivatization, enabling the construction of complex heterocyclic systems commonly found in medicinal chemistry. Its structure supports the design of compounds with improved lipophilicity and binding affinity, often explored in the research of CNS agents and kinase inhibitors.

shopping_cart Available Sizes & Pricing

Size Availability Unit Price Quantity
inventory 250mg
10-20 days ฿11,670.00
inventory 1g
10-20 days ฿31,500.00

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