4-(tert-Butoxycarbonyl)benzoic acid

95%

Reagent Code: #145504
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CAS Number 20576-82-3

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 222.24 g/mol
Formula C₁₂H₁₄O₄
thermostat Physical Properties
Melting Point 209-212°C
Boiling Point 351.8°C
inventory_2 Storage & Handling
Storage Room temperature, dry

description Product Description

Used as an intermediate in organic synthesis, particularly in the pharmaceutical industry for the preparation of active pharmaceutical ingredients (APIs). It serves as a protected form of 4-carboxybenzoic acid, where the tert-butoxycarbonyl (Boc) group acts as a protecting group for carboxylic acid functionalities during peptide synthesis and other multi-step syntheses. This allows selective reaction at other sites in the molecule without interference from the carboxylic acid group. After the desired transformations are complete, the Boc group can be easily removed under mild acidic conditions to regenerate the free carboxylic acid. Also employed in the synthesis of esters, amides, and heterocyclic compounds due to its stability and ease of handling.

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Size Availability Unit Price Quantity
inventory 1g
10-20 days ฿1,010.00

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