Benzyl 3,3-Difluorocyclobutanecarboxylate

≥95%

Reagent Code: #172205
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CAS Number 935273-86-2

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 226.22 g/mol
Formula C₁₂H₁₂F₂O₂
badge Registry Numbers
MDL Number MFCD18909480
inventory_2 Storage & Handling
Storage Room temperature, dry

description Product Description

Used as an intermediate in pharmaceutical synthesis, particularly in the development of bioactive molecules and drug candidates. Its strained cyclobutane ring and fluorinated substituents enhance metabolic stability and influence lipophilicity, making it valuable in medicinal chemistry for optimizing pharmacokinetic properties. The benzyl ester group facilitates protection of the carboxylic acid during synthetic transformations and can be selectively removed under mild conditions. Commonly employed in the preparation of protease inhibitors, receptor agonists, and other targeted therapies where fluorination improves binding affinity and resistance to oxidative degradation.

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Size Availability Unit Price Quantity
inventory 1g
10-20 days ฿6,990.00
inventory 5g
10-20 days ฿18,250.00

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