GW69A and GW554869A are primarily utilized in research settings to study their effects on metabolic pathways, particularly those related to lipid and glucose metabolism. They have been investigated for their potential role in modulating insulin sensitivity and improving metabolic disorders such as diabetes and obesity. Researchers often use them as tools to understand the mechanisms of action of certain receptors involved in these processes. Additionally, they have been explored for their possible application in developing therapeutic agents for metabolic syndrome and related conditions. Their use is confined to laboratory studies and preclinical research, with no current widespread clinical application.