(±)15-HETE is primarily used in research to study its role in inflammation and immune responses. It is involved in various biological processes, particularly in the regulation of leukocyte function and vascular permeability. Researchers utilize it to investigate its effects on signaling pathways, such as those involving lipoxygenase enzymes, and its potential impact on diseases like asthma, arthritis, and atherosclerosis. Additionally, it serves as a tool to explore its interactions with cellular receptors and its influence on oxidative stress and tissue repair mechanisms.