(±)11(12)-DiHETE is primarily used in research related to inflammation and cellular signaling pathways. It plays a role in studying the mechanisms of lipid mediators in various biological processes, particularly in the context of immune response and vascular function. Researchers utilize it to explore its effects on leukocyte behavior, endothelial cell interactions, and its potential involvement in resolving inflammation. Additionally, it is investigated for its impact on conditions such as atherosclerosis, asthma, and other inflammatory diseases. Its application extends to understanding the regulation of eicosanoid pathways and their influence on tissue homeostasis and repair.