Piperazine Erastin is primarily utilized in research settings to study ferroptosis, a form of regulated cell death characterized by iron-dependent lipid peroxidation. Its application is significant in understanding the mechanisms underlying ferroptosis and exploring its role in various diseases, including cancer and neurodegenerative disorders. Researchers use it to induce ferroptosis in cellular models, enabling the investigation of potential therapeutic targets and strategies to modulate this cell death pathway. Additionally, it aids in the development of compounds that can either inhibit or promote ferroptosis, offering insights into novel treatments for conditions where ferroptosis plays a critical role.