ICG-Sulfo-OSu sodium is widely used in biomedical imaging and diagnostics due to its near-infrared fluorescence properties. It is commonly employed as a labeling agent for proteins, peptides, and antibodies, enabling real-time tracking and visualization in biological systems. This compound is particularly valuable in fluorescence-guided surgeries, where it helps surgeons identify and remove tumors or abnormal tissues with precision. Additionally, it is utilized in molecular imaging studies to monitor cellular processes, drug delivery, and tissue targeting. Its water solubility and stability make it a preferred choice for in vivo imaging applications, including lymph node mapping and vascular imaging.