Used as a key intermediate in the synthesis of fluorinated pharmaceuticals, particularly in the development of enzyme inhibitors and bioactive molecules. Its rigid cyclobutane backbone and fluorine substituents enhance metabolic stability and binding selectivity. Commonly employed in medicinal chemistry for optimizing pharmacokinetic properties, such as membrane permeability and resistance to oxidative degradation. Also utilized in the design of peptidomimetics due to its structural similarity to amino acids, enabling incorporation into peptide chains to modulate biological activity.