2-Chloro-5-(fluorosulfonyl)benzoic acid
97%
Reagent
Code: #164414
CAS Number
21346-66-7
blur_circular Chemical Specifications
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Molecular Information
Weight
238.62 g/mol
Formula
C₇H₄ClFO₄S
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Registry Numbers
MDL Number
MFCD00007418
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Physical Properties
Melting Point
148-150 °C(lit.)
Boiling Point
370.0±32.0 °C(Predicted)
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Storage & Handling
Storage
Room temperature, inert gas
description Product Description
Used primarily as a key intermediate in the synthesis of pharmaceuticals and agrochemicals. Its reactive fluorosulfonyl group enables efficient sulfonamide and sulfonate ester formation, making it valuable in drug development. Commonly employed in the preparation of protease inhibitors and other bioactive molecules. Also utilized in materials science for modifying polymer surfaces due to its ability to introduce polar functional groups. Its high reactivity allows for selective derivatization in complex molecule assembly, especially in late-stage functionalization of active pharmaceutical ingredients (APIs).
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