diethyl (3-(trifluoromethyl)benzyl)phosphonate
≥95%
Reagent
Code: #168228
CAS Number
146780-08-7
science Other reagents with same CAS 146780-08-7
blur_circular Chemical Specifications
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Molecular Information
Weight
296.24 g/mol
Formula
C₁₂H₁₆F₃O₃P
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Storage & Handling
Storage
Room temperature, seal, dry
description Product Description
Used as a key intermediate in the synthesis of pharmaceuticals, particularly in the development of fluorinated analogs of bioactive molecules. Its structure enables the introduction of a trifluoromethyl-substituted benzyl group, which can enhance metabolic stability and lipophilicity in drug candidates. Commonly employed in Horner-Wadsworth-Emmons reactions to form fluorinated olefins, which are important motifs in medicinal chemistry. Also utilized in agrochemical research for designing novel active ingredients with improved environmental stability and biological activity.