tert-Butyl (3,3-difluorocyclobutyl)carbamate
98%
Reagent
Code: #150930
CAS Number
1029720-19-1
blur_circular Chemical Specifications
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Molecular Information
Weight
207.22 g/mol
Formula
C₉H₁₅F₂NO₂
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Registry Numbers
MDL Number
MFCD10001483
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Physical Properties
Boiling Point
254.0±40.0 °C(Predicted)
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Storage & Handling
Density
1.13±0.1 g/cm3(Predicted)
Storage
2-8°C
description Product Description
Used as an intermediate in pharmaceutical synthesis, particularly in the development of bioactive molecules requiring fluorinated cyclobutane moieties. The tert-butyl carbamate group serves as a protected amine, enabling selective reactions in multi-step organic syntheses. Its difluorocyclobutyl structure enhances metabolic stability and lipophilicity, making it valuable in medicinal chemistry for optimizing drug candidates. Commonly employed in the preparation of protease inhibitors and receptor modulators where ring strain and fluorine substitution influence potency and pharmacokinetics.
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