(9H-Fluoren-9-yl)methyl 3-hydroxyazetidine-1-carboxylate
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description Product Description
This compound, (9H-Fluoren-9-yl)methyl 3-hydroxyazetidine-1-carboxylate, is an Fmoc-protected 3-hydroxyazetidine derivative serving as a key building block in organic synthesis. The Fmoc group protects the azetidine nitrogen, enabling selective functionalization of the free hydroxyl group at the 3-position during multi-step reactions. It is particularly valuable in peptide synthesis, medicinal chemistry, and the construction of biologically active molecules, where the azetidine ring facilitates cyclization, ring-opening, or incorporation into complex scaffolds. The Fmoc protecting group provides stability under various conditions and can be orthogonally removed under mild basic conditions (e.g., piperidine in DMF), making it ideal for solid-phase synthesis and drug discovery applications.
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