m-PEG6-NHS ester is widely used in bioconjugation and chemical modification processes. It is particularly valuable in attaching polyethylene glycol (PEG) chains to proteins, peptides, or other biomolecules, enhancing their solubility, stability, and biocompatibility. This modification is crucial in drug delivery systems, where it helps reduce immunogenicity and prolong the circulation time of therapeutic agents. Additionally, it is employed in surface functionalization of nanoparticles and biomaterials, improving their performance in biomedical applications such as targeted drug delivery and diagnostic imaging. Its reactive NHS ester group ensures efficient and specific coupling with amine-containing molecules, making it a versatile tool in bioconjugation chemistry.