This chemical is primarily used as a reactive intermediate in the synthesis of polyethylene glycol (PEG) derivatives. Its application is significant in the field of bioconjugation, where it is employed to modify proteins, peptides, and other biomolecules to enhance their solubility, stability, and bioavailability. It is also utilized in the development of drug delivery systems, particularly in creating PEGylated therapeutics, which can improve the pharmacokinetic properties of drugs by prolonging their circulation time in the body. Additionally, it finds use in surface modification of materials, where it can impart hydrophilic properties to surfaces, making them more biocompatible and resistant to protein adsorption.