H2N-PEG24-CH2CH2COOtBu
95%
Reagent
Code: #108487
CAS Number
2170987-96-7
blur_circular Chemical Specifications
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Molecular Information
Weight
1202.46 g/mol
Formula
C₅₅H₁₁₁NO₂₆
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Registry Numbers
MDL Number
MFCD11041158
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Storage & Handling
Storage
2-8°C, sealed, dry
description Product Description
This chemical is widely used in bioconjugation and drug delivery systems due to its polyethylene glycol (PEG) chain, which enhances solubility and stability of biomolecules. The amine group (H2N-) allows for easy attachment to proteins, peptides, or other targeting molecules, while the t-butyl ester (COOtBu) provides a protective group that can be removed under specific conditions to expose a reactive carboxyl group. This makes it valuable in creating prodrugs or controlled-release formulations. Additionally, its long PEG spacer improves biocompatibility and reduces immunogenicity, making it suitable for therapeutic applications such as antibody-drug conjugates, nanoparticles, and targeted cancer therapies.
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H2N-PEG24-CH2CH2COOtBu
This chemical is widely used in bioconjugation and drug delivery systems due to its polyethylene glycol (PEG) chain, which enhances solubility and stability of biomolecules. The amine group (H2N-) allows for easy attachment to proteins, peptides, or other targeting molecules, while the t-butyl ester (COOtBu) provides a protective group that can be removed under specific conditions to expose a reactive carboxyl group. This makes it valuable in creating prodrugs or controlled-release formulations. Additionally, its long PEG spacer improves biocompatibility and reduces immunogenicity, making it suitable for therapeutic applications such as antibody-drug conjugates, nanoparticles, and targeted cancer therapies.
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