Mal-amide-PEG2-oxyamineBoc
≥95%
Reagent
Code: #108851
CAS Number
2253965-15-8
blur_circular Chemical Specifications
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Molecular Information
Weight
415.44 g/mol
Formula
C₁₈H₂₉N₃O₈
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Storage & Handling
Storage
2-8°C, sealed, dry
description Product Description
Mal-amide-PEG2-oxyamineBoc is widely used in bioconjugation and chemical biology for its ability to link biomolecules. Its mal-amide group reacts specifically with thiols, enabling the attachment of peptides, proteins, or other molecules containing cysteine residues. The PEG2 spacer enhances solubility and reduces steric hindrance, improving the efficiency of conjugation. The oxyamine group allows for selective reactions with aldehydes or ketones, often used in labeling or immobilizing biomolecules. The Boc (tert-butyloxycarbonyl) protecting group ensures stability during synthesis and can be removed under mild acidic conditions to expose the reactive oxyamine for further modifications. This compound is particularly valuable in the development of antibody-drug conjugates, protein labeling, and the creation of biomolecular probes for research and therapeutic applications. Its versatility makes it a key tool in targeted drug delivery and diagnostic studies.
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Mal-amide-PEG2-oxyamineBoc
Mal-amide-PEG2-oxyamineBoc is widely used in bioconjugation and chemical biology for its ability to link biomolecules. Its mal-amide group reacts specifically with thiols, enabling the attachment of peptides, proteins, or other molecules containing cysteine residues. The PEG2 spacer enhances solubility and reduces steric hindrance, improving the efficiency of conjugation. The oxyamine group allows for selective reactions with aldehydes or ketones, often used in labeling or immobilizing biomolecules. The Boc (tert-butyloxycarbonyl) protecting group ensures stability during synthesis and can be removed under mild acidic conditions to expose the reactive oxyamine for further modifications. This compound is particularly valuable in the development of antibody-drug conjugates, protein labeling, and the creation of biomolecular probes for research and therapeutic applications. Its versatility makes it a key tool in targeted drug delivery and diagnostic studies.
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