Amino-dPEG®8-acid is widely used in bioconjugation and chemical biology due to its water-soluble PEG spacer, which enhances solubility and reduces immunogenicity. It serves as a linker in the development of antibody-drug conjugates (ADCs), enabling targeted drug delivery to cancer cells. The compound is also utilized in peptide synthesis, where it improves the stability and bioavailability of therapeutic peptides. Additionally, it is employed in the creation of biosensors and diagnostic reagents, where its spacer arm facilitates proper orientation and functionality of biomolecules. Its application extends to surface modification of nanoparticles, enhancing their biocompatibility for drug delivery systems.