Amino-PEG8-amine is widely used in bioconjugation and chemical modification processes due to its bifunctional nature and hydrophilic polyethylene glycol (PEG) spacer. It serves as a linker in the synthesis of drug delivery systems, enabling the attachment of therapeutic agents to targeting molecules like antibodies or peptides. The PEG chain enhances solubility and reduces immunogenicity, making it valuable in creating biocompatible conjugates. It is also employed in surface modification of nanoparticles or biomaterials to improve stability and prolong circulation time in vivo. Additionally, it plays a role in crosslinking reactions for hydrogel formation, which is useful in tissue engineering and controlled release applications. Its versatility makes it a key component in developing advanced biomedical and pharmaceutical technologies.