This compound is widely utilized in bioconjugation and drug delivery systems due to its ability to enhance solubility and stability of therapeutic agents. It is commonly employed in modifying proteins, peptides, and antibodies to improve their pharmacokinetic properties, such as prolonged circulation time in the body. Additionally, it serves as a linker in antibody-drug conjugates (ADCs), facilitating the attachment of cytotoxic drugs to targeting molecules. Its application extends to the development of prodrugs, where it helps in controlled release of active pharmaceutical ingredients. Furthermore, it is used in surface modification of nanoparticles to enhance biocompatibility and reduce immunogenicity, making it valuable in nanomedicine and targeted therapy.